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Mechanical Overloading Induced-Activation of mTOR Signaling in Tendon Stem/Progenitor Cells Contributes to Tendinopathy Development

Despite the importance of mechanical loading in tendon homeostasis and pathophysiology, the molecular responses involved in the mechanotransduction in tendon cells remain unclear. In this study, we found that in vitro mechanical loading activated the mammalian target of rapamycin (mTOR) in rat patel...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Nie, Daibang, Zhou, Yiqin, Wang, Wang, Zhang, Jianying, Wang, James H.-C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8311934/
https://ncbi.nlm.nih.gov/pubmed/34322484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.687856
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