Divergent erythroid megakaryocyte fates in Blvrb-deficient mice establish non-overlapping cytoprotective functions during stress hematopoiesis

Cytoprotective mechanisms of heme oxygenases function by derivatizing heme to generate carbon monoxide, ferrous iron, and isomeric biliverdins, followed by rapid NAD(P)H-dependent biliverdin reduction to the antioxidant bilirubin using two non-overlapping biliverdin reductases that display biliverdi...

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Détails bibliographiques
Publié dans:Free Radic Biol Med
Auteurs principaux: Nesbitt, Natasha M., Malone, Lisa E., Liu, Zhaoyan, Jares, Alexander, Gnatenko, Dmitri V., Ma, Yupo, Zhu, Wei, Bahou, Wadie F.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8311568/
https://ncbi.nlm.nih.gov/pubmed/33359909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2020.12.015
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