RUNX1B Expression Is Highly Heterogeneous and Distinguishes Megakaryocytic and Erythroid Lineage Fate in Adult Mouse Hematopoiesis

The Core Binding Factor (CBF) protein RUNX1 is a master regulator of definitive hematopoiesis, crucial for hematopoietic stem cell (HSC) emergence during ontogeny. RUNX1 also plays vital roles in adult mice, in regulating the correct specification of numerous blood lineages. Akin to the other mammal...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Draper, Julia E., Sroczynska, Patrycja, Tsoulaki, Olga, Leong, Hui Sun, Fadlullah, Muhammad Z. H., Miller, Crispin, Kouskoff, Valerie, Lacaud, Georges
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726605/
https://ncbi.nlm.nih.gov/pubmed/26808730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005814
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