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Differential Scanning Fluorimetry and Hydrogen Deuterium Exchange Mass Spectrometry to Monitor the Conformational Dynamics of NBD1 in Cystic Fibrosis

Cystic fibrosis (CF) is one of the most common, lethal autosomal recessive disease in the Caucasians with a life expectancy of 37-47 years. The CF transmembrane conductance regulator (CFTR) is a plasma membrane ion channel, confined to apical membrane of epithelia, and ensures transepithelial water...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Methods Mol Biol
Main Authors: Soya, Naoto, Roldan, Ariel, Lukacs, Gergely L.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8311558/
https://ncbi.nlm.nih.gov/pubmed/30341603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-8820-4_4
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