Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating

Enterovirus uncoating receptors bind at the surface depression (“canyon”) that encircles each capsid vertex causing the release of a host-derived lipid called “pocket factor” that is buried in a hydrophobic pocket formed by the major viral capsid protein, VP1. Coxsackievirus and adenovirus receptor...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Xu, Longfa, Zheng, Qingbing, Zhu, Rui, Yin, Zhichao, Yu, Hai, Lin, Yu, Wu, Yuanyuan, He, Maozhou, Huang, Yang, Jiang, Yichao, Sun, Hui, Zha, Zhenghui, Yang, Hongwei, Huang, Qiongzi, Zhang, Dongqing, Chen, Zhenqin, Ye, Xiangzhong, Han, Jinle, Yang, Lisheng, Liu, Che, Que, Yuqiong, Fang, Mujin, Gu, Ying, Zhang, Jun, Luo, Wenxin, Zhou, Z. Hong, Li, Shaowei, Cheng, Tong, Xia, Ningshao
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310385/
https://ncbi.nlm.nih.gov/pubmed/33539764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2021.01.001
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