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Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody

Coxsackievirus A6 (CVA6) has recently emerged as a major cause of hand, foot and mouth disease in children worldwide but no vaccine is available against CVA6 infections. Here, we demonstrate the isolation of two forms of stable CVA6 particles-procapsid and A-particle-with excellent biochemical stabi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Xu, Longfa, Zheng, Qingbing, Li, Shaowei, He, Maozhou, Wu, Yangtao, Li, Yongchao, Zhu, Rui, Yu, Hai, Hong, Qiyang, Jiang, Jie, Li, Zizhen, Li, Shuxuan, Zhao, Huan, Yang, Lisheng, Hou, Wangheng, Wang, Wei, Ye, Xiangzhong, Zhang, Jun, Baker, Timothy S., Cheng, Tong, Zhou, Z. Hong, Yan, Xiaodong, Xia, Ningshao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593947/
https://ncbi.nlm.nih.gov/pubmed/28894095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00477-9
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