Adeno-Associated Virus (AAV) Gene Delivery: Dissecting Molecular Interactions upon Cell Entry

Human gene therapy has advanced from twentieth-century conception to twenty-first-century reality. The recombinant Adeno-Associated Virus (rAAV) is a major gene therapy vector. Research continues to improve rAAV safety and efficacy using a variety of AAV capsid modification strategies. Significant f...

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Enregistré dans:
Détails bibliographiques
Publié dans:Viruses
Auteurs principaux: Large, Edward E., Silveria, Mark A., Zane, Grant M., Weerakoon, Onellah, Chapman, Michael S.
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310307/
https://ncbi.nlm.nih.gov/pubmed/34372542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13071336
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