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Modulation of Viral Programmed Ribosomal Frameshifting and Stop Codon Readthrough by the Host Restriction Factor Shiftless

The product of the interferon-stimulated gene C19orf66, Shiftless (SHFL), restricts human immunodeficiency virus replication through downregulation of the efficiency of the viral gag/pol frameshifting signal. In this study, we demonstrate that bacterially expressed, purified SHFL can decrease the ef...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Napthine, Sawsan, Hill, Chris H., Nugent, Holly C. M., Brierley, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310280/
https://ncbi.nlm.nih.gov/pubmed/34202160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13071230
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