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Comprehensive Profiling of Mutations to Influenza Virus PB2 That Confer Resistance to the Cap-Binding Inhibitor Pimodivir

Antivirals are used not only in the current treatment of influenza but are also stockpiled as a first line of defense against novel influenza strains for which vaccines have yet to be developed. Identifying drug resistance mutations can guide the clinical deployment of the antiviral and can addition...

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Publicado en:Viruses
Autores principales: Soh, Y. Q. Shirleen, Malone, Keara D., Eguia, Rachel T., Bloom, Jesse D.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310130/
https://ncbi.nlm.nih.gov/pubmed/34206520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13071196
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