Development of a Novel Live Attenuated Influenza A Virus Vaccine Encoding the IgA-Inducing Protein

Live attenuated influenza virus (LAIV) vaccines elicit a combination of systemic and mucosal immunity by mimicking a natural infection. To further enhance protective mucosal responses, we incorporated the gene encoding the IgA-inducing protein (IGIP) into the LAIV genomes of the cold-adapted A/Lenin...

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Vydáno v:Vaccines (Basel)
Hlavní autoři: Cáceres, C. Joaquín, Cardenas-Garcia, Stivalis, Jain, Aarti, Gay, L. Claire, Carnaccini, Silvia, Seibert, Brittany, Ferreri, Lucas M., Geiger, Ginger, Jasinskas, Algimantas, Nakajima, Rie, Rajao, Daniela S., Isakova-Sivak, Irina, Rudenko, Larisa, Vincent, Amy L., Davies, D. Huw, Perez, Daniel R.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310050/
https://ncbi.nlm.nih.gov/pubmed/34198994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines9070703
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