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Rapid and Sensitive Quantification of Intracellular Glycyl-Sarcosine for Semi-High-Throughput Screening for Inhibitors of PEPT-1

The peptide transporter PEPT-1 (SLC15A1) plays a major role in nutritional supply with amino acids by mediating the intestinal influx of dipeptides and tripeptides generated during food digestion. Its role in the uptake of small bioactive peptides and various therapeutics makes it an important targe...

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Publicado en:Pharmaceutics
Main Authors: von Linde, Teresa, Bajraktari-Sylejmani, Gzona, Haefeli, Walter E., Burhenne, Jürgen, Weiss, Johanna, Sauter, Max
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8309108/
https://ncbi.nlm.nih.gov/pubmed/34371711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13071019
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