Development of a Cyclodextrin-Based Mucoadhesive-Thermosensitive In Situ Gel for Clonazepam Intranasal Delivery

A thermosensitive, mucoadhesive in-situ gel for clonazepam (CLZ) intranasal delivery was developed, which aimed to achieve prolonged in-situ residence and controlled drug release, overcoming problems associated with its oral or parenteral administration. Poloxamer was selected as a thermosensitive p...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Cirri, Marzia, Maestrelli, Francesca, Nerli, Giulia, Mennini, Natascia, D’Ambrosio, Mario, Luceri, Cristina, Mura, Paola Angela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8309035/
https://ncbi.nlm.nih.gov/pubmed/34206967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13070969
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