Thermosensitive and Mucoadhesive Sol-Gel Composites of Paclitaxel/Dimethyl-β-Cyclodextrin for Buccal Delivery

The purpose of this study was to develop a buccal paclitaxel delivery system using the thermosensitive polymer Pluronic F127 (PF127) and the mucoadhesive polymer polyethylene oxide (PEO). The anticancer agent paclitaxel is usually used to treat ovarian, breast, and non-small-cell lung cancer. To imp...

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Bibliografiske detaljer
Main Authors: Choi, Soon Gil, Lee, Sang-Eun, Kang, Bong-Seok, Ng, Choon Lian, Davaa, Enkhzaya, Park, Jeong-Sook
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183572/
https://ncbi.nlm.nih.gov/pubmed/25275485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109090
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