Thermosensitive and Mucoadhesive Sol-Gel Composites of Paclitaxel/Dimethyl-β-Cyclodextrin for Buccal Delivery

The purpose of this study was to develop a buccal paclitaxel delivery system using the thermosensitive polymer Pluronic F127 (PF127) and the mucoadhesive polymer polyethylene oxide (PEO). The anticancer agent paclitaxel is usually used to treat ovarian, breast, and non-small-cell lung cancer. To imp...

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Detalhes bibliográficos
Main Authors: Choi, Soon Gil, Lee, Sang-Eun, Kang, Bong-Seok, Ng, Choon Lian, Davaa, Enkhzaya, Park, Jeong-Sook
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183572/
https://ncbi.nlm.nih.gov/pubmed/25275485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109090
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