Discovery and Characterization of a Novel MASTL Inhibitor MKI-2 Targeting MASTL-PP2A in Breast Cancer Cells and Oocytes

Although microtubule-associated serine/threonine kinase-like (MASTL) is a promising target for selective anticancer treatment, MASTL inhibitors with nano range potency and antitumor efficacy have not been reported. Here, we report a novel potent and selective MASTL inhibitor MASTL kinase inhibitor-2...

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Vydáno v:Pharmaceuticals (Basel)
Hlavní autoři: Kang, Minsung, Kim, Chijung, Leem, Jiyeon, Kim, Ye-hyun, Kwon, Young-ju, Yoon, Yi Na, Chae, Chong Hak, Ahn, Jiyeon, Jung, Kwan-Young, Oh, Jeong Su, Kim, Jae-Sung
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308786/
https://ncbi.nlm.nih.gov/pubmed/34358073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14070647
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