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Synthesis and Human Carbonic Anhydrase I, II, IX, and XII Inhibition Studies of Sulphonamides Incorporating Mono-, Bi- and Tricyclic Imide Moieties

New derivatives were synthesised by reaction of amino-containing aromatic sulphonamides with mono-, bi-, and tricyclic anhydrides. These sulphonamides were investigated as human carbonic anhydrases (hCAs, EC 4.2.1.1) I, II, IX, and XII inhibitors. hCA I was inhibited with inhibition constants (Kis)...

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Bibliografische gegevens
Gepubliceerd in:Pharmaceuticals (Basel)
Hoofdauteurs: Sethi, Kalyan K., Mishra, KM Abha, Verma, Saurabh M., Vullo, Daniela, Carta, Fabrizio, Supuran, Claudiu T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308639/
https://ncbi.nlm.nih.gov/pubmed/34358123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14070693
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