تحميل...
Design and Synthesis of Novel Thiazolo[5,4-d]pyrimidine Derivatives with High Affinity for Both the Adenosine A(1) and A(2A) Receptors, and Efficacy in Animal Models of Depression
New compounds with a 7-amino-2-arylmethyl-thiazolo[5,4-d]pyrimidine structure were synthesized and evaluated in vitro for their affinity and/or potency at the human (h) A(1), hA(2A), hA(2B), and hA(3) adenosine receptors (ARs). Several compounds (5, 8–10, 13, 18, 19) were characterized by nanomolar...
محفوظ في:
| الحاوية / القاعدة: | Pharmaceuticals (Basel) |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
MDPI
2021
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8308585/ https://ncbi.nlm.nih.gov/pubmed/34358083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14070657 |
| الوسوم: |
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