3,4-Difluorobenzocurcumin Inhibits Vegfc-Vegfr3-Erk Signalling to Block Developmental Lymphangiogenesis in Zebrafish

Lymphangiogenesis, the formation of new lymphatic vessels from pre-existing vasculature, plays critical roles in disease, including in cancer metastasis and chronic inflammation. Preclinical and recent clinical studies have now demonstrated therapeutic utility for several anti-lymphangiogenic agents...

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Bibliografiske detaljer
Udgivet i:Pharmaceuticals (Basel)
Main Authors: Okuda, Kazuhide S., Ng, Mei Fong, Ruslan, Nur Faizah, Bower, Neil I., Song, Dedrick Soon Seng, Chen, Huijun, Baek, Sungmin, Crosier, Philip S., Koltowska, Katarzyna, Astin, Jonathan W., Tan, Pei Jean, Hogan, Benjamin M., Patel, Vyomesh
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308560/
https://ncbi.nlm.nih.gov/pubmed/34206901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14070614
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