Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk

Lymphatic vascular development involves specification of lymphatic endothelial progenitors that subsequently undergo sprouting, proliferation and tissue growth to form a complex second vasculature. The Hippo pathway and effectors Yap and Taz control organ growth and regulate morphogenesis and cellul...

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Vydáno v:eLife
Hlavní autoři: Grimm, Lin, Nakajima, Hiroyuki, Chaudhury, Smrita, Bower, Neil I, Okuda, Kazuhide S, Cox, Andrew G, Harvey, Natasha L, Koltowska, Katarzyna, Mochizuki, Naoki, Hogan, Benjamin M
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516831/
https://ncbi.nlm.nih.gov/pubmed/31038457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42881
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