Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk

Lymphatic vascular development involves specification of lymphatic endothelial progenitors that subsequently undergo sprouting, proliferation and tissue growth to form a complex second vasculature. The Hippo pathway and effectors Yap and Taz control organ growth and regulate morphogenesis and cellul...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Grimm, Lin, Nakajima, Hiroyuki, Chaudhury, Smrita, Bower, Neil I, Okuda, Kazuhide S, Cox, Andrew G, Harvey, Natasha L, Koltowska, Katarzyna, Mochizuki, Naoki, Hogan, Benjamin M
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2019
Fag:
Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516831/
https://ncbi.nlm.nih.gov/pubmed/31038457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42881
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