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Vegfc acts through ERK to induce sprouting and differentiation of trunk lymphatic progenitors
Vascular endothelial growth factor C (Vegfc) activates its receptor, Flt4, to induce lymphatic development. However, the signals that act downstream of Flt4 in this context in vivo remain unclear. To understand Flt4 signaling better, we generated zebrafish bearing a deletion in the Flt4 cytoplasmic...
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Publicado no: | Development |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Company of Biologists Ltd
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087638/ https://ncbi.nlm.nih.gov/pubmed/27621059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.137901 |
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