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Vegfc acts through ERK to induce sprouting and differentiation of trunk lymphatic progenitors
Vascular endothelial growth factor C (Vegfc) activates its receptor, Flt4, to induce lymphatic development. However, the signals that act downstream of Flt4 in this context in vivo remain unclear. To understand Flt4 signaling better, we generated zebrafish bearing a deletion in the Flt4 cytoplasmic...
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| Pubblicato in: | Development |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087638/ https://ncbi.nlm.nih.gov/pubmed/27621059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.137901 |
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