A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis

Platelet-derived growth factor B (PDGF-B) is a mitogenic, migratory and survival factor. Cell-associated PDGF-B recruits stabilizing pericytes towards blood vessels through retention in extracellular matrix. We hypothesized that the genetic ablation of cell-associated PDGF-B by retention motif delet...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Tillie, Renée J. H. A., Theelen, Thomas L., van Kuijk, Kim, Temmerman, Lieve, de Bruijn, Jenny, Gijbels, Marion, Betsholtz, Christer, Biessen, Erik A. L., Sluimer, Judith C.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308020/
https://ncbi.nlm.nih.gov/pubmed/34359916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071746
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker