Computational design of a synthetic PD-1 agonist

Programmed cell death protein-1 (PD-1) expressed on activated T cells inhibits T cell function and proliferation to prevent an excessive immune response, and disease can result if this delicate balance is shifted in either direction. Tumor cells often take advantage of this pathway by overexpressing...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bryan, Cassie M., Rocklin, Gabriel J., Bick, Matthew J., Ford, Alex, Majri-Morrison, Sonia, Kroll, Ashley V., Miller, Chad J., Carter, Lauren, Goreshnik, Inna, Kang, Alex, DiMaio, Frank, Tarbell, Kristin V., Baker, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8307378/
https://ncbi.nlm.nih.gov/pubmed/34272285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2102164118
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados