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Global analysis of protein folding using massively parallel design, synthesis and testing

Proteins fold into unique native structures stabilized by thousands of weak interactions that collectively overcome the entropic cost of folding. Though these forces are “encoded” in the thousands of known protein structures, “decoding” them is challenging due to the complexity of natural proteins t...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Rocklin, Gabriel J., Chidyausiku, Tamuka M., Goreshnik, Inna, Ford, Alex, Houliston, Scott, Lemak, Alexander, Carter, Lauren, Ravichandran, Rashmi, Mulligan, Vikram K., Chevalier, Aaron, Arrowsmith, Cheryl H., Baker, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568797/
https://ncbi.nlm.nih.gov/pubmed/28706065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan0693
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