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Search for Novel Lead Inhibitors of Yeast Cytochrome bc1, from Drugbank and COCONUT

In this work we introduce a novel filtering and molecular modeling pipeline based on a fingerprint and descriptor similarity procedure, coupled with molecular docking and molecular dynamics (MD), to select potential novel quoinone outside inhibitors (QoI) of cytochrome bc1 with the aim of determinin...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Jović, Ozren, Šmuc, Tomislav
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8307329/
https://ncbi.nlm.nih.gov/pubmed/34299598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26144323
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