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Constipation induced gut microbiota dysbiosis exacerbates experimental autoimmune encephalomyelitis in C57BL/6 mice

BACKGROUND: Constipation is a common gastrointestinal dysfunction which has a potential impact on people's immune state and their quality of life. Here we investigated the effects of constipation on experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). MET...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Lin, Xiuli, Liu, Yingying, Ma, Lili, Ma, Xiaomeng, Shen, Liping, Ma, Xueying, Chen, Zhaoyu, Chen, Hao, Li, Donghong, Su, Zhumin, Chen, Xiaohong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306367/
https://ncbi.nlm.nih.gov/pubmed/34301274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02995-z
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