Constipation induced gut microbiota dysbiosis exacerbates experimental autoimmune encephalomyelitis in C57BL/6 mice

BACKGROUND: Constipation is a common gastrointestinal dysfunction which has a potential impact on people's immune state and their quality of life. Here we investigated the effects of constipation on experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). MET...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Lin, Xiuli, Liu, Yingying, Ma, Lili, Ma, Xiaomeng, Shen, Liping, Ma, Xueying, Chen, Zhaoyu, Chen, Hao, Li, Donghong, Su, Zhumin, Chen, Xiaohong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306367/
https://ncbi.nlm.nih.gov/pubmed/34301274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02995-z
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