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SAP Suppresses the Development of Experimental Autoimmune Encephalomyelitis in C57BL6 Mice

Experimental autoimmune encephalomyelitis (EAE) is a CD4(+) T cell-mediated disease of the CNS. Serum amyloid P component (SAP) is a highly conserved plasma protein named for its universal presence in amyloid deposits. Here we report SAP transgenic mice had unexpectedly attenuated EAE due to impaire...

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Detalhes bibliográficos
Main Authors: Ji, Zhe, Ke, Zun-Ji, Geng, Jian-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880774/
https://ncbi.nlm.nih.gov/pubmed/21647172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2011.51
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