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Regulation of Mitochondrial Respiration by VDAC Is Enhanced by Membrane-Bound Inhibitors with Disordered Polyanionic C-Terminal Domains

The voltage-dependent anion channel (VDAC) is the primary regulating pathway of water-soluble metabolites and ions across the mitochondrial outer membrane. When reconstituted into lipid membranes, VDAC responds to sufficiently large transmembrane potentials by transitioning to gated states in which...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Rostovtseva, Tatiana K., Bezrukov, Sergey M., Hoogerheide, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306229/
https://ncbi.nlm.nih.gov/pubmed/34298976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147358
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