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Exploring lipid-dependent conformations of membrane-bound α-synuclein with the VDAC nanopore
Regulation of VDAC by α-Synuclein (αSyn) is a rich and instructive example of protein-protein interactions catalyzed by a lipid membrane surface. αSyn, a peripheral membrane protein involved in Parkinson’s disease pathology, is known to bind to membranes in a transient manner. αSyn’s negatively char...
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| Publicado en: | Biochim Biophys Acta Biomembr |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8255272/ https://ncbi.nlm.nih.gov/pubmed/33971161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2021.183643 |
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