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Design and heterologous expression of a novel dimeric LL37 variant in Pichia pastoris

BACKGROUND: The antimicrobial peptide LL37 is produced by white blood cells (mainly neutrophils) and various epithelial cells, and has the outstanding advantages of participating in immune regulation, causing chemotaxis of immune cells and promoting wound healing. However, the central domain of LL37...

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Bibliografische gegevens
Gepubliceerd in:Microb Cell Fact
Hoofdauteurs: Zhan, Na, Zhang, Licong, Yang, Hong, Zheng, Yalan, Wei, Xinke, Wang, Jiajun, Shan, Anshan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305873/
https://ncbi.nlm.nih.gov/pubmed/34301247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-021-01635-x
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