Expression and Purification of Hybrid LL-37Tα1 Peptide in Pichia pastoris and Evaluation of Its Immunomodulatory and Anti-inflammatory Activities by LPS Neutralization

This study pertains to the new approach for the development of hybrid peptide LL-37Tα1 and its biomedical applications. A linear cationic hybrid peptide, LL-37Tα1 was derived from two parental peptides (LL-37 and Tα1) recognized as potent anti-endotoxin without any hemolytic or cytotoxic activity. W...

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Vydáno v:Front Immunol
Hlavní autoři: Ahmad, Baseer, Hanif, Quratulain, Xubiao, Wei, Lulu, Zhang, Shahid, Muhammad, Dayong, Si, Rijun, Zhang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587124/
https://ncbi.nlm.nih.gov/pubmed/31258535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01365
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