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A Small Protein but with Diverse Roles: A Review of EsxA in Mycobacterium–Host Interaction
As a major effector of the ESX-1 secretion system, EsxA is essential for the virulence of pathogenic mycobacteria, such as Mycobacterium tuberculosis (Mtb) and Mycobacterium marinum (Mm). EsxA possesses an acidic pH-dependent membrane permeabilizing activity and plays an essential role by mediating...
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| Publié dans: | Cells |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8305481/ https://ncbi.nlm.nih.gov/pubmed/34209120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071645 |
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