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Characterization of Mycobacterium tuberculosis EsxA Membrane Insertion: ROLES OF N- AND C-TERMINAL FLEXIBLE ARMS AND CENTRAL HELIX-TURN-HELIX MOTIF
EsxA (ESAT-6), an important virulence factor of Mycobacterium tuberculosis, plays an essential role in phagosome rupture and bacterial cytosolic translocation within host macrophages. Our previous study showed that EsxA exhibits a unique membrane-interacting activity that is not found in its ortholo...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4358149/ https://ncbi.nlm.nih.gov/pubmed/25645924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.622076 |
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