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Targeting Glucose Metabolism of Cancer Cells with Dichloroacetate to Radiosensitize High-Grade Gliomas

As the cornerstone of high-grade glioma (HGG) treatment, radiotherapy temporarily controls tumor cells via inducing oxidative stress and subsequent DNA breaks. However, almost all HGGs recur within months. Therefore, it is important to understand the underlying mechanisms of radioresistance, so that...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cook, Kristina M., Shen, Han, McKelvey, Kelly J., Gee, Harriet E., Hau, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305417/
https://ncbi.nlm.nih.gov/pubmed/34298883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147265
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