Synthesis and Cytotoxicity Evaluation of Spirocyclic Bromotyrosine Clavatadine C Analogs

Marine-originated spirocyclic bromotyrosines are considered as promising scaffolds for new anticancer drugs. In a continuation of our research to develop potent and more selective anticancer compounds, we synthesized a library of 32 spirocyclic clavatadine analogs by replacing the agmatine, i.e., 4-...

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Detaylı Bibliyografya
Yayımlandı:Mar Drugs
Asıl Yazarlar: Patel, Piyush A., Bruun, Tanja, Ilina, Polina, Mäkkylä, Heidi, Lempinen, Antti, Yli-Kauhaluoma, Jari, Tammela, Päivi, Kiuru, Paula S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305101/
https://ncbi.nlm.nih.gov/pubmed/34356825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md19070400
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