Practical High-Throughput Method to Screen Compounds for Anthelmintic Activity against Caenorhabditis elegans

In the present study, we established a practical and cost-effective high throughput screening assay, which relies on the measurement of the motility of Caenorhabditis elegans by infrared light-interference. Using this assay, we screened 14,400 small molecules from the “HitFinder” library (Maybridge)...

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Bibliographic Details
Published in:Molecules
Main Authors: Taki, Aya C., Byrne, Joseph J., Boag, Peter R., Jabbar, Abdul, Gasser, Robin B.
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305057/
https://ncbi.nlm.nih.gov/pubmed/34299431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26144156
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