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Practical High-Throughput Method to Screen Compounds for Anthelmintic Activity against Caenorhabditis elegans

In the present study, we established a practical and cost-effective high throughput screening assay, which relies on the measurement of the motility of Caenorhabditis elegans by infrared light-interference. Using this assay, we screened 14,400 small molecules from the “HitFinder” library (Maybridge)...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Taki, Aya C., Byrne, Joseph J., Boag, Peter R., Jabbar, Abdul, Gasser, Robin B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305057/
https://ncbi.nlm.nih.gov/pubmed/34299431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26144156
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