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Effects of Mutations in TSC Genes on Neurodevelopment and Synaptic Transmission

Mutations in TSC1 or TSC2 genes are linked to alterations in neuronal function which ultimately lead to the development of a complex neurological phenotype. Here we review current research on the effects that reduction in TSC1 or TSC2 can produce on the developing neural network. A crucial feature o...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bassetti, Davide, Luhmann, Heiko J., Kirischuk, Sergei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305053/
https://ncbi.nlm.nih.gov/pubmed/34298906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147273
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