RANBP2 Activates O-GlcNAcylation through Inducing CEBPα-Dependent OGA Downregulation to Promote Hepatocellular Carcinoma Malignant Phenotypes

SIMPLE SUMMARY: Hepatocellular carcinoma (HCC) is characterized by a poor prognosis and high mortality rate, with complex molecular alterations, including glycosylation. O-linked N-acetylglucosamine (O-GlcNAc) is a dynamic modification process jointly controlled by the “writer” O-GlcNAc transferase...

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Udgivet i:Cancers (Basel)
Main Authors: Liu, Xiaoming, Chen, Xingyu, Xiao, Mengqing, Zhu, Yuxing, Gong, Renjie, Liu, Jianye, Zeng, Qinghai, Xu, Canxia, Chen, Xiong, Wang, Fen, Cao, Ke
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304650/
https://ncbi.nlm.nih.gov/pubmed/34298689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143475
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