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New In Vitro-In Silico Approach for the Prediction of In Vivo Performance of Drug Combinations

Pharmacokinetic (PK) studies improve the design of dosing regimens in preclinical and clinical settings. In complex diseases like cancer, single-agent approaches are often insufficient for an effective treatment, and drug combination therapies can be implemented. In this work, in silico PK models we...

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書目詳細資料
發表在:Molecules
Main Authors: Correia, Cristiana, Ferreira, Abigail, Santos, Joana, Lapa, Rui, Yliperttula, Marjo, Urtti, Arto, Vale, Nuno
格式: Artigo
語言:Inglês
出版: MDPI 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304213/
https://ncbi.nlm.nih.gov/pubmed/34299532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26144257
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