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New In Vitro-In Silico Approach for the Prediction of In Vivo Performance of Drug Combinations

Pharmacokinetic (PK) studies improve the design of dosing regimens in preclinical and clinical settings. In complex diseases like cancer, single-agent approaches are often insufficient for an effective treatment, and drug combination therapies can be implemented. In this work, in silico PK models we...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Correia, Cristiana, Ferreira, Abigail, Santos, Joana, Lapa, Rui, Yliperttula, Marjo, Urtti, Arto, Vale, Nuno
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304213/
https://ncbi.nlm.nih.gov/pubmed/34299532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26144257
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