Peripheral Opioid Receptor Blockade Enhances Epithelial Damage in Piroxicam-Accelerated Colitis in IL-10-Deficient Mice

Mucosal CD4(+) T lymphocytes display a potent opioid-mediated analgesic activity in interleukin (IL)-10 knockout mouse model of inflammatory bowel diseases (IBD). Considering that endogenous opioids may also exhibit anti-inflammatory activities in the periphery, we examined the consequences of a per...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mas-Orea, Xavier, Sebert, Morgane, Benamar, Mehdi, Petitfils, Camille, Blanpied, Catherine, Saoudi, Abdelhadi, Deraison, Céline, Barreau, Frederick, Cenac, Nicolas, Dietrich, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304158/
https://ncbi.nlm.nih.gov/pubmed/34299013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147387
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