Short Chain Fatty Acid Acetate Increases TNFα-Induced MCP-1 Production in Monocytic Cells via ACSL1/MAPK/NF-κB Axis

Short-chain fatty acid (SCFA) acetate, a byproduct of dietary fiber metabolism by gut bacteria, has multiple immunomodulatory functions. The anti-inflammatory role of acetate is well documented; however, its effect on monocyte chemoattractant protein-1 (MCP-1) production is unknown. Similarly, the c...

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Publicat a:Int J Mol Sci
Autors principals: Al-Roub, Areej, Akhter, Nadeem, Al-Sayyar, Amnah, Wilson, Ajit, Thomas, Reeby, Kochumon, Shihab, Al-Rashed, Fatema, Al-Mulla, Fahd, Sindhu, Sardar, Ahmad, Rasheed
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304091/
https://ncbi.nlm.nih.gov/pubmed/34299302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147683
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