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Cholate Disrupts Regulatory Functions of Cytochrome c Oxidase

Cytochrome c oxidase (CytOx), the oxygen-accepting and rate-limiting enzyme of mitochondrial respiration, binds with 10 molecules of ADP, 7 of which are exchanged by ATP at high ATP/ADP-ratios. These bound ATP and ADP can be exchanged by cholate, which is generally used for the purification of CytOx...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Ramzan, Rabia, Napiwotzki, Jörg, Weber, Petra, Kadenbach, Bernhard, Vogt, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303988/
https://ncbi.nlm.nih.gov/pubmed/34201437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071579
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