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Revisiting Kadenbach: Electron flux rate through cytochrome c‐oxidase determines the ATP‐inhibitory effect and subsequent production of ROS

Mitochondrial respiration is the predominant source of ATP. Excessive rates of electron transport cause a higher production of harmful reactive oxygen species (ROS). There are two regulatory mechanisms known. The first, according to Mitchel, is dependent on the mitochondrial membrane potential that...

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Detalhes bibliográficos
Publicado no:Bioessays
Main Authors: Vogt, Sebastian, Rhiel, Annika, Weber, Petra, Ramzan, Rabia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084804/
https://ncbi.nlm.nih.gov/pubmed/27171124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201600043
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