Tyrosine Phosphoproteomics of Patient-Derived Xenografts Reveals Ephrin Type-B Receptor 4 Tyrosine Kinase as a Therapeutic Target in Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic cancer is one of the deadliest solid malignancies. Pancreatic ductal adenocarcinoma accounts for 90% of pancreatic cancer cases with minimal response to traditional chemotherapies. Protein tyrosine kinases have been shown to be hyperactivated in cancers and thus can serve...

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Publicado no:Cancers (Basel)
Main Authors: Renuse, Santosh, Madamsetty, Vijay S., Mun, Dong-Gi, Madugundu, Anil K., Singh, Smrita, Udainiya, Savita, Mangalaparthi, Kiran K., Kim, Min-Sik, Liu, Ren, Kumar, S. Ram, Krasnoperov, Valery, Truty, Mark, Graham, Rondell P., Gill, Parkash S., Mukhopadhyay, Debabrata, Pandey, Akhilesh
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303779/
https://ncbi.nlm.nih.gov/pubmed/34298619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143404
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