Analysis of Genetic Variants Associated with Levels of Immune Modulating Proteins for Impact on Alzheimer’s Disease Risk Reveal a Potential Role for SIGLEC14

Genome-wide association studies (GWAS) have identified immune-related genes as risk factors for Alzheimer’s disease (AD), including TREM2 and CD33, frequently passing a stringent false-discovery rate. These genes either encode or signal through immunomodulatory tyrosine-phosphorylated inhibitory mot...

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Bibliografiske detaljer
Udgivet i:Genes (Basel)
Main Authors: Shaw, Benjamin C., Katsumata, Yuriko, Simpson, James F., Fardo, David W., Estus, Steven
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303736/
https://ncbi.nlm.nih.gov/pubmed/34208838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12071008
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