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Functional Roles of Bromodomain Proteins in Cancer

SIMPLE SUMMARY: This review provides an in depth analysis of the role of bromodomain-containing proteins in cancer development. As readers of acetylated lysine on nucleosomal histones, bromodomain proteins are poised to activate gene expression, and often promote cancer progression. We examined chan...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Boyson, Samuel P., Gao, Cong, Quinn, Kathleen, Boyd, Joseph, Paculova, Hana, Frietze, Seth, Glass, Karen C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303718/
https://ncbi.nlm.nih.gov/pubmed/34298819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143606
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