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The emerging roles of CDK12 in tumorigenesis

Cyclin-dependent kinases (CDKs) are key regulators of both cell cycle progression and transcription. Since dysregulation of CDKs is a frequently occurring event driving tumorigenesis, CDKs have been tested extensively as targets for cancer therapy. Cyclin-dependent kinase 12 (CDK12) is a transcripti...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Div
Auteurs principaux: Paculová, Hana, Kohoutek, Jiří
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658942/
https://ncbi.nlm.nih.gov/pubmed/29090014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13008-017-0033-x
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