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Effects of (R)- and (S)-α-Hydroxylation of Acyl Chains in Sphingosine, Dihydrosphingosine, and Phytosphingosine Ceramides on Phase Behavior and Permeability of Skin Lipid Models

Ceramides (Cers) with α-hydroxylated acyl chains comprise about a third of all extractable skin Cers and are required for permeability barrier homeostasis. We have probed here the effects of Cer hydroxylation on their behavior in lipid models comprising the major SC lipids, Cer/free fatty acids (C (...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Kováčik, Andrej, Pullmannová, Petra, Opálka, Lukáš, Šilarová, Michaela, Maixner, Jaroslav, Vávrová, Kateřina
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303283/
https://ncbi.nlm.nih.gov/pubmed/34299088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147468
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