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Identification of Insulin-Mimetic Plant Extracts: From an In Vitro High-Content Screen to Blood Glucose Reduction in Live Animals

Type 2 diabetes mellitus (T2DM) is linked to insulin resistance and a loss of insulin sensitivity, leading to millions of deaths worldwide each year. T2DM is caused by reduced uptake of glucose facilitated by glucose transporter 4 (GLUT4) in muscle and adipose tissue due to decreased intracellular t...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Stadlbauer, Verena, Neuhauser, Cathrina, Aumiller, Tobias, Stallinger, Alexander, Iken, Marcus, Weghuber, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303208/
https://ncbi.nlm.nih.gov/pubmed/34299620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26144346
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