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ER – lysosome contacts at a pre-axonal region regulate axonal lysosome availability

Neuronal function relies on careful coordination of organelle organization and transport. Kinesin-1 mediates transport of the endoplasmic reticulum (ER) and lysosomes into the axon and it is increasingly recognized that contacts between the ER and lysosomes influence organelle organization. However,...

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發表在:Nat Commun
Main Authors: Özkan, Nazmiye, Koppers, Max, van Soest, Inge, van Harten, Alexandra, Jurriens, Daphne, Liv, Nalan, Klumperman, Judith, Kapitein, Lukas C., Hoogenraad, Casper C., Farías, Ginny G.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302662/
https://ncbi.nlm.nih.gov/pubmed/34301956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24713-5
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