Preexisting heart failure with reduced ejection fraction attenuates renal fibrosis after ischemia reperfusion via sympathetic activation

Although chronic heart failure is clinically associated with acute kidney injury (AKI), the precise mechanism that connects kidney and heart remains unknown. Here, we elucidate the effect of pre-existing heart failure with reduced ejection fraction (HFrEF) on kidney via sympathetic activity, using t...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Matsuura, Ryo, Yamashita, Tetsushi, Hayase, Naoki, Hamasaki, Yoshifumi, Noiri, Eisei, Numata, Genri, Takimoto, Eiki, Nangaku, Masaomi, Doi, Kent
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302613/
https://ncbi.nlm.nih.gov/pubmed/34302012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94617-3
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